Anticomplement activity of lysine complexes of propolis phenolic constituents and their synthetic analogs.
نویسندگان
چکیده
Several phenolic constituents of propolis and their synthetic analogs were derivatized with L-lysine. The ability of these complexes to alter complement activity was estimated in vitro in human serum. The influence of selected complexes on C3 hemolytic activity via classical pathway (CP) and alternative pathway (AP) and on zymosan-induced AP activation was determined. The results suppose that the anticomplement effect of the complexes might be related to the interaction with C3 complement component.
منابع مشابه
A GC/MS Study of the Propolis Phenolic Constituents
Propolis is a resinous hive product Kv bees. The versatile biological activities of propolis, such as its antibacterial, antiviral, fungicidal, anti ulcer, immunostimulating, hypotensive and cytosta tic properties, as well as its successful clinical applica tions [1 — 3] have created an increasing interest in its chemical composition. The last appears to be very complex — the bees collect pr...
متن کاملVolatile Constituents of Propolis
Propolis (bee glue) is a resinous hive product, collected by bees. It possesses versatile biological activity antibacterial, antiviral, fungicidal, anti ulcer, immunostimulating, hypotensive, cytostatic, etc. [1]. The chemical com position of propolis ap peared to be very complex at least 156 propolis constituents have been identified so far [2,3]. M ost im portant constituents of propolis ap...
متن کاملSeasonal Variation, Chemical Composition and Antioxidant activity of Brazilian Propolis Samples
Total phenolic contents, antioxidant activity and chemical composition of propolis samples from three localities of Minas Gerais state (southeast Brazil) were determined. Total phenolic contents were determined by the Folin-Ciocalteau method, antioxidant activity was evaluated by DPPH, using BHT as reference, and chemical composition was analyzed by GC/MS. Propolis from Itapecerica and Paula Câ...
متن کاملChemical Composition and Antimicrobial Activities of Iranian Propolis
Background: With considering the importance of natural products for their remedial and therapeutic value, this research was aimed to analyze the chemical compositions and antimicrobial activity of four propolis samples from different areas of Iran (Chenaran, Taleghan, Morad Beyg, and Kalaleh) with various climates and flora. Methods: Ethanolic (70% EtOH) and dichlromethane (DCM) extracts of Ira...
متن کاملFrom functional food to medicinal product: Systematic approach in analysis of polyphenolics from propolis and wine
In the last decade we have been working on standardization of propolis extract and determination of active constituents of wine those are rich in polyphenolics and have nutritional as well as therapeutic value. Here we are summarizing our results and providing overview on systematic approach how to analyse natural products rich in flavonoids and phenolic acids.Chromatographic methods (thin laye...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Zeitschrift fur Naturforschung. C, Journal of biosciences
دوره 52 1-2 شماره
صفحات -
تاریخ انتشار 1997